WASHINGTON — U.S. Trade Representative Jamieson Greer announced Friday that his office will launch several new investigations under Section 301 of the Trade Act of 1974. The probes will cover most major U.S. trading partners. Topics range from pharmaceutical pricing and forced labor to industrial excess capacity and unfair treatment of U.S. tech companies and digital goods.

Greer spoke hours after the Supreme Court struck down tariffs ranging from 10% to 50% that President Trump had imposed under the International Emergency Economic Powers Act. Those tariffs, known as reciprocal and fentanyl duties, aimed to counter unfair trade practices. The ruling prompted Trump to invoke Section 301 instead. He also ordered a temporary 10% global import duty for 150 days.

“Our partners have been responsive and engaged in good-faith negotiations despite the pending litigation,” Greer said. “We are confident that all trade agreements negotiated by President Trump will remain in effect.” He stressed the Supreme Court decision affects only the IEEPA tariffs. Extensive duties under other laws stay intact.

The administration has secured framework trade deals with a dozen countries, according to the Council on Foreign Relations. It has signed full agreements with seven more. Trump warned foreign partners and businesses for months about shifting to tools like Section 301 if courts blocked the IEEPA measures.

Greer outlined broad potential focus areas. Investigators could examine digital services taxes, ocean pollution, and trade practices involving seafood and rice. The USTR plans an accelerated timeline for these reviews. Tariffs remain one option if unfair practices emerge.

Separate ongoing Section 301 probes already target Brazil and China. Those could yield tariffs too, Greer noted, should violations be confirmed. Trump issued his Section 301 order Friday without specifics on targets or timelines.

The moves come amid a turbulent week for U.S. trade policy. The Supreme Court ruling disrupted Trump’s tariff strategy but opened doors to statutory alternatives. Officials expressed optimism about preserving deals from Trump’s first term, including those with India, where Trump said Friday that nothing changes.

Business groups watched closely. Some praised the flexibility. Others worried about renewed trade friction with allies like Mexico and Canada, which recently won exemptions from a separate 10% U.S. levy. Risks linger for the USMCA pact.

Greer emphasized continuity. His office will push forward regardless of court outcomes. The Section 301 tool allows the president to respond to foreign practices burdening U.S. commerce, from subsidies to intellectual property theft.

Indonesia provides a recent success story. It signed a deal slashing tariffs to 19%. Similar outcomes could follow these probes, officials hope. Trump also directed agencies Friday to release files on UFOs and aliens, signaling a wide-ranging agenda.

Markets reacted swiftly. U.S. Treasuries fell after the court decision. A Cuba-bound tanker with Russian fuel tested Trump’s blockade plans. Visa revocations hit Chilean officials over a China cable project.

Tourism slumps persist in America, down 11 million visitors. These trade actions could ripple into broader economic ties. Greer gave no exact start dates for the new investigations but promised quick action.