The Vatican said in a statement that “based on his current clinical status, as well as the instrumental and laboratory tests performed, there are no contraindications that would prevent him from undertaking his upcoming apostolic journey.” Surgeons diagnosed Leo with lung adenocarcinoma, the most common form of lung cancer, during the operation. Since returning to the Vatican, he has gradually resumed duties, including his weekly audience in St. Peter’s Square.

The South America trip, covering Uruguay, Argentina and Peru, is one of the most demanding foreign journeys for a Catholic leader in decades. It includes 10 cities, 14 flights, and 36 speeches over 31,000 km. The Vatican confirmed the itinerary will proceed as previously published, including a visit to Cuzco, Peru, located at more than 11,000 feet above sea level.

Last week, the Vatican announced that Leo had canceled a planned visit to Assisi due to medical advice. Doctors advised against a helicopter journey because of the unpressurized air, which could have posed risks to his recovery. The Assisi trip had been scheduled for Oct. 27 to mark the 40th anniversary of St. John Paul II’s World Day of Prayer for Peace.

The South America trip holds personal significance for Leo, who spent more than two decades as a missionary and bishop in Peru before being called back to Rome in 2023. “I am looking forward to returning to the continent where I’ve experienced so many moments of my life,” he said in a Vatican statement. “May this journey be an occasion for us to open our hearts to one another, strengthen our communion as brothers and sisters, and renew our commitment to proclaiming the Gospel with joy.”

The Vatican said the pope is adjusting his schedule in consultation with his doctors to prioritize recovery while continuing to fulfill his ministerial responsibilities. On Oct. 25, he addressed the faithful in St. Peter’s Square but canceled the Assisi visit following medical advice.

The Vatican confirmed that the pope’s medical team has not identified any contraindications for the trip. His personal physician, Luigi Carbone, said the latest medical examinations show a favorable clinical condition. The Vatican also emphasized that Leo is following medical recommendations with “great care and diligence.”